Differences Between CBD and THC: Do you need THC in your CBD supplement?

CBD and THC are both cannabinoids, the active compounds that provide the effects from ingesting cannabis. Adding cannabinoids like CBD to your diet is acknowledged as beneficial to supporting homeostasis in the body. However, there are many opinions on the ideal way to supplement your diet with cannabinoids. Here we will compare CBD and THC and help you decide whether you will want to use an isolated CBD or full-spectrum hemp oil product.


As we mentioned above, both CBD and THC are cannabinoids – or more specifically, phytocannabinoids since they are plant based. While THC is most plentiful in marijuana, CBD is present in higher quantities in hemp. We further compare hemp and marijuana here.

One of the key differences between CBD and THC when it comes to hemp oil supplements is that, unlike THC, cannabidiol or CBD is non-psychoactive. THC or tetrahydrocannabinol is the chemical compound in cannabis that is responsible for producing euphoric effects. However, in CBD hemp oil products, THC is present in only trace levels, far below the psychoactive threshold. Because CBD produces no side effects, it is regarded as safe for use by anyone in your family.

Both CBD and THC interact with the body’s endocannabinoid system through specialized cannabinoid receptors to provide their effects, mimicking our own naturally occurring cannabinoids. There are two main types of cannabinoid receptors, CB1 and CB2. CB1 receptors are primarily located in the brain, male and female reproductive organs, eye, and more. CB2 receptors are located within the immune system, with a great density of receptors occurring in the spleen.

THC has a highest affinity for binding with CB1 receptors. CBD on the other hand doesn’t bind directly to either cannabinoid receptors. Instead, it acts indirectly against cannabinoid agonists. CBD also interacts with various other receptors throughout the body, like the 5-HT1A receptor, which is linked to serotonin. It is through this interaction with various systems within the body that these cannabinoids promote balance in our lives. Although they interact with the body through different channels, both THC and CBD are tied to maintaining homeostasis.

Entourage Effect

It has been suggested that the cannabinoids in cannabis work best when they interact with your body as a group, along with the terpenes, flavonoids, and other chemical components found naturally in the plant. This is commonly called the entourage effect.

Pure CBD hemp oil contains a number of different cannabinoids at varying levels as well as all the other natural components of the hemp plant. This allows the body to process the hemp oil as it would the complete hemp plant.

Many of HempMeds® CBD oil products feature full-spectrum hemp oil that includes all the same constituents as the hemp plant itself, providing the varied cannabinoids the entourage effect needs to be effective.

CBD Isolate

However, it is also possible to create CBD products like RSHO-X™ that are completely THC-free for those customers looking to avoid even trace levels of THC. This is done by isolating the CBD from the original hemp oil.

Like RSHO™ hemp oil, CBD isolate is extracted from non-GMO hemp using supercritical CO2. The CBD hemp oil is then purified using a proprietary process to filter plant material and winterized to remove excess waxes, producing a pure isolate powder with 99% CBD.

Because it is completely THC-free, HempMeds® CBD isolate is safe for use by all customers, including those subject to drug screenings that check for THC.

Which is Best for Me?

Like with all our products, the ideal HempMeds® product is a personal choice. Many of our customers prefer the experience they get with a full-spectrum hemp oil product like our original RSHO™ or Dixie Botanicals® products. However, there are those who instead prefer a CBD supplement that is completely free of THC like RSHO-X™ Liquid.

Regardless of which CBD hemp oil product from HempMeds® you purchase, you can be assured of its quality because we hold ourselves to the high standard of being Your Trusted CBD Source.

Discover more about CBD hemp oil products on our education page, or shop our online store to get started with CBD supplements today.





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