What is Clinical Endocannabinoid Deficiency Syndrome?

Health issues can arise when your body’s endocannabinoid system doesn’t get an adequate amount of cannabinoids to keep your functions balanced.

Your ability to maintain health and wellness is dependent on the performance of one of your body’s major regulatory networks, the endocannabinoid system. This major regulatory network is crucial to keeping many of your functions in balance and operating efficiently.

This system is so crucial that researchers have suggested that the underlying cause of many issues related to health and wellness have to do with a syndrome related to a dysfunction in the endocannabinoid system, which is referred to as clinical endocannabinoid deficiency syndrome.

Here we discuss clinical endocannabinoid deficiency syndrome and how cannabinoid supplements like CBD can help support the performance of your body’s endocannabinoid system.

A Quick Review of the Endocannabinoid System

Before going into clinical endocannabinoid deficiency syndrome, it is important that you first understand the endocannabinoid system and its role in health and wellness.

The endocannabinoid system is one of the body’s major signaling networks and it is tasked with regulating a wide array of body processes and keeping them in balance. Functions like mood and stress management, sleep, immune function, metabolism, memory, energy balance, and more are regulated and kept in homeostasis by the endocannabinoid system.

This means that various day-to-day functions, such as your ability to maintain proper energy levels, how effectively you can manage a healthy body weight, and the level at which you’re able to control stressful situations, are impacted by the efficiency of your endocannabinoid system.

Found in all mammals, the endocannabinoid system is made up of several integrated mechanisms, including:

  • Endocannabinoids: Cannabinoids naturally produced by the body
  • Enzymes: Substances responsible for creating and destroying cannabinoids
  • Cannabinoid receptors: Receptor sites found on cells in the central nervous system and immune system

Together, these three mechanisms are predominantly responsible for regulating body processes and functions. When in imbalance is detected, the endocannabinoids, synthesized and broken down as needed by enzymes, interact with cannabinoid receptors to trigger chemical reactions that help the body achieve homeostasis, or equilibrium.

While researchers continue to learn more how the endocannabinoid system contributes to the body’s central functions, they do know that a properly functioning endocannabinoid system keeps many of your body’s functions running smoothly and balanced. Whenever one of the body’s major functions gets out of balanced due to the outside environment, the endocannabinoid system takes the necessary steps to return to balance.

endocannabinoid system deficienc

Clinical Endocannabinoid Deficiency

First proposed in 2004 by renowned cannabinoid researcher Dr. Ethan Russo, the theory of clinical endocannabinoid deficiency syndrome, or CED, suggests that deficient cannabinoid levels can cause the endocannabinoid system to not operate properly, allowing for various functions to become unbalanced and issues to arise.

The idea is that without an optimal level of cannabinoids, the endocannabinoid system is unable to properly stimulate cannabinoid receptors when an imbalance is detected.

Russo and his colleagues came up with the theory after examining the available literature and finding evidence that certain issues were associated with lower levels of cannabinoids. They concluded that these problems likely develop when a person is starved of cannabinoids.

In a reexamination of CED in 2016, Russo explained that the syndrome could arise from various causes, including:

  • Disease
  • Injury or infection
  • Genetic predisposition
  • Congenital causes

Clinical endocannabinoid deficiency may also be related to an overall lack of plant-derived cannabinoids in today’s diet. Some plants, including cannabis plants like hemp, are optimal sources of cannabinoids. While once a staple in America and throughout the world, cannabis has for decades been eliminated from contemporary human diets, potentially contributing to the occurrence of cannabinoid deficits.

Russo, in his research, went on to suggest that supplementing with plant-based nutritional cannabinoids could address CED by stimulating the endocannabinoid system and support its efforts to keep the body balanced.

CBD Augments Endocannabinoids

Plant-derived cannabinoids like CBD may be beneficial for supporting the endocannabinoid system and potentially maintaining optimal health. Analogous to the endocannabinoids naturally produced by the body, CBD and cannabinoids like it interact with the cannabinoid receptors of the endocannabinoid system. By stimulating cannabinoid receptors, CBD can augment the body’s own endocannabinoids to support the performance of the endocannabinoid system.

Derived from cannabis plants like hemp, CBD has become a popular daily supplement among those looking to stimulate their systems. While there are over 100 different cannabinoids so far identified in cannabis by scientists, CBD is by far one of the most abundant, as well as among the most extensively studied and best understood.

hemp cannabinoid deficiency

CBD can be extracted from the hemp plant in the form of high-CBD hemp oil. Once this pure hemp extract is tested for safety, quality, and cannabinoid content, it can be consumed directly as a supplement or infused into various types of products, like CBD capsules, CBD liquids, CBD tinctures, and CBD topicals, or filtered to create a 99% pure CBD isolate.

CBD oil also contains various dietary nutrients that support health. Hemp-derived CBD oil is a good source of essential vitamins and minerals, fatty acids, protein, chlorophyll, flavonoids, and terpenes that align with a routine designed to support health and wellness.

While CBD interacts with the body’s naturally occurring endocannabinoid system, it is non-psychotropic, so it doesn’t cause a high. This means that CBD is a safer and less controversial way for people of all ages to support the endocannabinoid system with cannabis.

This is why the benefits of CBD oil supplements are not just for people facing adverse health conditions. Even if you’re healthy, CBD’s balancing properties and the nutritional content of hemp oil helps ensure your body is given what it needs to stay healthy over the years.

Supplement with CBD

The introduction of plant-derived cannabinoids like CBD may augment the body’s own endocannabinoids and help bring the body back into balance. You can learn more about the natural benefits of CBD by visiting the HempMeds® blog.

Get started supplementing your systems with CBD today through the HempMeds® online shop.

To learn more about HempMeds® wholesale opportunities, visit HERE, or call us at 866-273-8502 to speak with a wholesale specialist. You can also join our affiliate program.

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